|
KMID : 0858520170210020091
|
|
Journal of the Korean Society of Magnetic Resonance in Medicine
2017 Volume.21 No. 2 p.91 ~ p.96
|
|
|
Functional Magnetic Resonance Imaging with Arterial Spin Labeling: Techniques and Potential Clinical and Research Applications
|
|
Kim Ju-Ho
Choi Dae-Seob
Park Sung-Eun
Choi Ho-Cheol
Kim Seong-Hu
|
|
|
Abstract
|
|
|
Purpose: To describe technical methods for functional magnetic resonance imaging (fMRI) study with arterial spin labeling (ASL) compared to blood oxygenation level-dependent (BOLD) technique and discuss the potential of ASL for research and clinical practice.
Materials and Methods: Task-based (n = 1) and resting-state fMRI (rs-fMRI) (n = 20) were performed using ASL and BOLD techniques. Results of both techniques were compared.
Results: For task-based fMRI with finger-tapping, the primary motor cortex of the contralateral frontal lobe and the ipsilateral cerebellum were activated by both BOLD and ASL fMRI. For rs-fMRI of sensorimotor network, functional connectivity showed similar results between BOLD and ASL.
Conclusion: ASL technique has potential application in clinical and research fields because all brain perfusion imaging, CBF measurement, and rs-fMRI study can be performed in a single acquisition.
|
|
|
KEYWORD
|
|
|
Cerebral blood flow (CBF), Arterial spin labeling (ASL), Blood oxygenation level-dependent (BOLD), Functional MRI (fMRI), Resting state fMRI
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|